Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image
Acne Phage Serum Main Image

4.5
Rated 4.5 out of 5 stars
1,466 Reviews

Our phages kill hormonal and cystic acne by targeting only your acne-causing bacteria.  The beauty of this technology is that it doesn’t kill your good bacteria so you don’t get those annoying side effects and relapses.

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$70

$59

ONE TIME PURCHASE

$70

HSA / FSA ELIGIBLE

60-DAY GUARANTEE

ZERO SIDE EFFECTS
ZERO REDNESS
ZERO IRRITATION
ZERO PEELING
ZERO SENSITIVITY
ZERO BURNING
ZERO BENZENE
EFFECTIVE AGAINST: HORMONAL ACNE
CYSTIC ACNE
BLACKHEADS
WHITEHEADS
INFLAMMATORY ACNE
NODULAR ACNE
TEEN ACNE
ZERO SIDE EFFECTS
ZERO REDNESS
ZERO IRRITATION
ZERO PEELING
ZERO SENSITIVITY
ZERO BURNING
ZERO BENZENE
EFFECTIVE AGAINST: HORMONAL ACNE
CYSTIC ACNE
BLACKHEADS
WHITEHEADS
INFLAMMATORY ACNE
NODULAR ACNE
TEEN ACNE
ZERO SIDE EFFECTS
ZERO REDNESS
ZERO IRRITATION
ZERO PEELING
ZERO SENSITIVITY
ZERO BURNING
ZERO BENZENE
EFFECTIVE AGAINST: HORMONAL ACNE
CYSTIC ACNE
BLACKHEADS
WHITEHEADS
INFLAMMATORY ACNE
NODULAR ACNE
TEEN ACNE

“My skin is not only clearer but overall looks more alive than ever.”

– Emory P.

Before

Before Image

After 4 Weeks

After Image

“Two months of using Phyla and I am finally feeling confident again.”

– Alexandra L.

Hormonal acne

Before

Before Image

After 8 Weeks

After Image

“Phyla is the only product I have ever used that has helped with my acne.”

– Sam b.

Cystic Acne

Before

Before Image

After 8 Weeks

After Image
serum

Acne Phage Serum

An advanced acne treatment powered by phages to eliminate acne, fade post-acne marks, and restore your skin’s microbiome balance for clear skin that lasts.

In an independent, third-party, placebo-controlled, double-blind consumer testing panel involving 90 participants aged 12-35:

90%

Reduction in acne-causing bacteria (C. acnes) after just 8 weeks of use.

100%

of participants reported no side effects.

93%

Reported healthier-looking skin by week 4

97%

experienced a boost in confidence after 8 weeks of using Phyla.

Inactive Ingredients: Water, Glycerin, Butylene Glycol, Hydroxyethylcellulose, C. Acnes Bacteriophage, Sodium Phosphate, Sodium Chloride, Phenoxyethanol, Polydextrose, Sclerotium Gum, Niacinamide, Magnesium Sulfate, Caffeine, Calcium Chloride

Active Ingredient: 0.5% Salicylic Acid

  • Cleanse skin thoroughly before use.

  • Apply a thin layer to the entire face and affected area twice daily, in the morning and night.

  • Can be applied to both the face and body, wherever breakouts occur.

  • Tip:
    Healthy skin has phages, while acne-prone skin doesn’t. Phyla is phages in a bottle. By adding phages to your daily skincare routine, you’re boosting your skin’s microbiome and paving the way for clear, balanced skin for life.

In an independent, third-party, placebo-controlled, double-blind consumer testing panel involving 90 participants aged 12-35:

90%

Reduction in acne-causing bacteria (C. acnes) after just 8 weeks of use.

100%

of participants reported no side effects.

93%

Reported healthier-looking skin by week 4

97%

experienced a boost in confidence after 8 weeks of using Phyla.

Inactive Ingredients: Water, Glycerin, Butylene Glycol, Hydroxyethylcellulose, C. Acnes Bacteriophage, Sodium Phosphate, Sodium Chloride, Phenoxyethanol, Polydextrose, Sclerotium Gum, Niacinamide, Magnesium Sulfate, Caffeine, Calcium Chloride

Active Ingredient: 0.5% Salicylic Acid

  • Cleanse skin thoroughly before use.

  • Apply a thin layer to the entire face and affected area twice daily, in the morning and night.

  • Can be applied to both the face and body, wherever breakouts occur.

  • Tip:
    Healthy skin has phages, while acne-prone skin doesn’t. Phyla is phages in a bottle. By adding phages to your daily skincare routine, you’re boosting your skin’s microbiome and paving the way for clear, balanced skin for life.

Phages clear hormonal and cystic and teen acne with no side effects.

serum bottle image
Dotted shape image

Our patented phage technology precisely targets acne-causing bacteria (C.Acnes) while nurturing your skin’s microbiome.

SEE PHAGES AT WORK

Acne Phage Ration Image

Start seeing results within 2 weeks

90

%

Reduction in acne
bacteria on skin

93

%

Reported healthier
looking skin by 4 weeks

100

%

Free from side effects

The only solution for healthy, acne-free skin.

BENZOYL PEROXIDE ACCUTANE ANTIBIOTICS Treats Acne Zero Side Effects Kills ONLY Acne Bacteria Doesn’t Damage Good Bacteria Prevents Acne Free of Benzene Recommended by Dermatologists Patented Technology
Benzoyl peroxide Accutane Antibiotics
Treats Acne
Zero Side Effects
Kills ONLY Acne Bacteria
Doesn’t Damage Good Bacteria
Prevents Acne
Free of Benzene
Recommended by Dermatologists
Patented Technology
Reviewer transformation image

It has literally changed my life

“i've tried everything...This product not only helps my day-to-day acne,but my hormonal ance as well, which even tretinion did'nt do.”

– ellie

Reviewer transformation image

This stuff is a game-changer

“I have struggled with severe acne for years and this has gotten rid of all of [may acne].It's truly so amazing and it does'nt dehydrate my skin at all.”

– scarlette e

Reviewer transformation image

Finally feeling confident

“About a year ago i got off [hormonal birth control] and my face looked like a pubescent kid who washes their face in crisco.Two months of using Phyla and I am finally feeling confident again”

– Alexandra L

Reviewer transformation image

The results are incredible

“Beyond grateful and relieved...I experienced acne in my 20s and was so insecure...and decided to give one last product a try.”

– candice t.

Custom Section Image

Use twice daily

Morning + Night

4.5
Rated 4.5 out of 5 stars
Based on 1,466 reviews
Total 5 star reviews: 977 Total 4 star reviews: 317 Total 3 star reviews: 121 Total 2 star reviews: 30 Total 1 star reviews: 21
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1,466 reviews
  • Serena S.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range 25 - 34
    Skin Type Combination
    Type of Acne Hormonal
    Rated 4 out of 5 stars
    1 month ago
    Great product to combat adult acne

    I have been desperate in looking for an adult acne solution that is natural and works from the inside out. Phyla has been a great help. I just finished my first shipment of it, and have noticed that my breakouts are a lot less painful and big. The whipped moisturizer is especially soothing and calming! The the Phages serum has a great feel, and seems to really be working. I’m still having some hormonal acne, so curious to see how a second round of the Phage serum continues to help uproot the acne!

    Attached are photos from when I started the system to today.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    2 weeks ago

    We are so glad to hear you are seeing progress, Serena! With prolonged use of the Serum, you are gradually adding the phages back to your skin so they can naturally occur there. The more you continue this, the better the results! Thanks for sharing :)

  • Kimberly C.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range 25 - 34
    Skin Type Oily
    Type of Acne Hormonal
    Rated 5 out of 5 stars
    2 months ago
    60 day review

    After around 60 days of usage, I think the phyla serum is working. I am still experiencing some cystic/hormonal acne; however, I do feel like the occurrence is reduced and I plan on continuing the treatment for an additional 60 days.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    2 months ago

    Hi Kimberly! Thank you so much for sharing your 60-day update along with your pictures! Those results are amazing! We’re thrilled to hear you’re seeing progress and that the frequency of breakouts has been reduced. Consistency is key, so we’re excited that you’re continuing with the treatment for another 60 days. Please keep us posted on your results!

  • Kristen O.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range 35 - 44
    Skin Type Combination
    Type of Acne Hormonal
    Rated 5 out of 5 stars
    2 months ago
    Gentle and Effective

    I love the three step program. It’s simple and easy to use. I really enjoy keeping the serum cool in my refrigerator. It’s refreshing on my skin and it seems to genuinely help calm my breakouts and prevent them from escalating into a full-blown war on my face. the moisturizer smells amazing. I wish you made one in a larger size

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    2 months ago

    Hi Kristen! Thank you for sharing your experience! We’re so glad to hear that you love the three-step program and that it’s helping calm your breakouts. It’s great to know you’re enjoying the refreshing feel of the cool serum and the amazing scent of the moisturizer!

  • Katie M.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range 35 - 44
    Skin Type Sensitive
    Type of Acne Hormonal
    Rated 5 out of 5 stars
    2 months ago
    Great products

    I'm loving this system! The cleanser isn't too drying and gets my skin feeling clean and fresh. I use twice daily as instructed. The serum is so nice when it's cold (as instructed) and makes my skin feel empowered and fresh. The whipped moisturizer is so lovely and soft. I love how it makes my skin feel like new skin. So soft and hydrated. I use everything twice daily, and it is doing a great job. When I have a breakout, the products help move things along faster. I also feel like there's less scarring from breakouts. Hormonal breakouts suck, but I have a powerful and beautiful system to help. Thank you Phage!

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    2 months ago

    Hi Katie! Thank you so much for your wonderful feedback! We’re thrilled to hear how much you're enjoying the system and that it’s making a difference with your hormonal breakouts. It’s great to know the products are helping you feel empowered and refreshed! We truly appreciate your support and look forward to continuing to help you on your skincare journey.

  • Jennifer M.
    Verified Buyer
    Onward VIP Protection+
    Reviewing
    Onward VIP Protection+
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Best Acne Fighter out there!!!

    I suffer from PCOS as well as an Autoimmune disease that causes psoriasis. This product never irritates me and always solves my acne problems. If at first you don’t notice any results, do not give up!! Remember - you are basically evolving the bacteria on your skin to be healthier and nicer!! This takes time :-) Always a returning customer.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    2 months ago

    Hi Jennifer! Thank you so much for your kind words and for sharing your experience with Phyla! I’m thrilled to hear that it’s been a great solution for your acne, especially with your PCOS and autoimmune condition. Your advice to be patient is spot on, as balancing the skin’s bacteria does take time. We’re so grateful to have you as a returning customer!

  • Kathryn O.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage Serum (60 Day Supply)
    Reviewing
    Acne-Fighting Phage Serum (60 Day Supply)
    I recommend this product
    Age Range 25 - 34
    Skin Type Combination
    Type of Acne Hormonal
    Rated 4 out of 5 stars
    3 months ago
    So far so good

    My skin felt healthier after just one use. It’s a bit challenging to get one pump to cover my whole face but eventually I got the hang of it. My skin has improved since starting this serum, it’s still not perfect but I’ve had much less irritation even when using other actives along with phyla. I’m going to keep using it.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    3 months ago

    Hi Kathryn! I’m so glad to hear that your skin felt healthier after just one use and that you've noticed less irritation since using our serum! It’s great that you're getting the hang of applying the perfect amount! If you need any tips on application or product use, feel free to reach out. We’re here to support you every step of the way! Esthetician@phitherapeutics.com

  • Amanda Y.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range 18 - 24
    Skin Type Combination
    Type of Acne Cystic
    Rated 5 out of 5 stars
    3 months ago
    Smooth

    I've tried many different skin products trying to nullify how dry my skin gets but then goes straight to oil. The moisturizer is my favorite so far. It has a very smooth texture and no oily feel some others I've tried has.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    3 months ago

    Hi Amanda! I’m so glad to hear that you’re enjoying the texture of our moisturizer and that it’s helping with your skin’s dryness without feeling oily. We appreciate your support and your feedback means a lot to us!

  • Meredith M.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage Serum (60 Day Supply)
    Reviewing
    Acne-Fighting Phage Serum (60 Day Supply)
    I recommend this product
    Age Range 45 - 54
    Skin Type Combination
    Type of Acne Hormonal
    Rated 4 out of 5 stars
    3 months ago
    A solid start

    This hasn’t -hurt- my skin, and my middle-age acne is definitely improved in a big way in the last six weeks—believe it or not from the pic, but this is so much better! (And this is without makeup—all these spots are flat and disappear with just a light foundation). It’s not as fast or complete a turnaround as I’ve had with prescription antibiotic treatment, but this also seems far more sustainable for the long run on many levels. I’m looking forward to the next round! (Just a note—I was glad to discover on the site that you don’t have to refrigerate it 100% of the time—I travel for work and was concerned about consistency. *That being said, a travel size would be awesome, Phyla!*

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    3 months ago

    Hello Meredith! Thank you so much for sharing your experience! We’re thrilled to hear that your skin has improved, and you’re right! Phyla is designed not just for acne relief, but to help create healthy, balanced skin in the long run. While prescription treatments may offer faster results, Phyla’s microbiome-focused approach is more sustainable for your skin’s overall health, supporting it in a way that’s gentler and long-lasting.

    We also appreciate your suggestion for a travel size—that’s definitely something worth considering! Thank you for your thoughtful feedback, and we’re excited to see how your skin continues to improve!

  • sara s.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage System (60 Day Supply)
    Reviewing
    Acne-Fighting Phage System (60 Day Supply)
    I recommend this product
    Age Range Under 18
    Skin Type Combination
    Type of Acne Hormonal
    Rated 5 out of 5 stars
    3 months ago
    phyla is amazing

    Phyla was amazing. I had tons of rosacea and acne all over my cheeks and less than two weeks. It was mostly all disappeared and made my skin look so good and smooth and feel so good and smooth. I love phyla and I’m definitely gonna purchase it more.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    3 months ago

    Hi Sara! Thank you so much for sharing your results with us! We love to hear that your results happened so quick!

  • Sasha C.
    Flag of United States
    Verified Buyer
    Acne-Fighting Phage Serum (60 Day Supply)
    Reviewing
    Acne-Fighting Phage Serum (60 Day Supply)
    I recommend this product
    Age Range 35 - 44
    Skin Type Combination
    Type of Acne Cystic
    Rated 5 out of 5 stars
    3 months ago
    So far so good!

    I love the reclosable bottle that the surround comes in. It is extremely easy to apply and I’ve had no negative side effects. I feel like my skin has had some improvement since I started using it, reduced large cystic acne, and I’m looking forward to seeing how it improves in another month of use.

    PS Profile picture for Phyla Skincare
    Phyla Skincare
    3 months ago

    Hi Sasha! Thanks for the kind words! We are happy to hear you are seeing results so quickly!

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